When a blood vessel is hurt, blood comes out. However, if the wound is small, the blood stops oozing out after some time. Platelets and clotting factors are responsible for clotting the blood and in turn stopping the blood flow. Platelets form a platelet plug at the wounded place to stop the flow. Thus it seals the wound. But if the plug remains immobile for the prolonged period, then, clots may form in the blood vessels. The clots may also get dislodged and flow in the blood supply.
They may get into the important organs like heart, lungs or brain. Hampered blood flow can create many medical ailments related to these organs. Also, internal injuries may also cause blood clots. Blood thinners are drugs that prevent clot formation or dissolve blood clots in the blood supply. Drugs which Blood thinners are used to reduce the risk of blood clots that may lead to a cardiac arrest and other medical conditions like brain hemorrhage.
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There are many Blood thinners in clinical trials, and many are there at different stages of pre-clinical development. Many blood thinners are still in pipeline which indicates that the market of blood thinners is likely to rise in the forecast period 2016-2024. The market for blood thinners is analogous to the medical, biologics, pharmaceuticals and biotechnology market. Increasing incidences of heart diseases, changing lifestyle and eating habits will drive the market of blood thinners ahead. The restraining factors in the blood thinners market may be ethical issues or the regulatory reforms of particular countries/ regions that restrict the sale or clinical trials of blood thinners in that region. Also, upcoming alternatives for blood thinners can pose to be restraining for the blood thinner market.
The blood thinners are of two types. Anticoagulants like heparin or warfarin (which is also called as Coumadin), they act on the chemical reactions taking place in the body to extend the time taken for blood clotting. Antiplatelet drugs like aspirin prevent the platelets to form clumps together to form a clot. Injectable blood thinners include low molecular weight heparin, lepirudin, danaparoid, argatroban, drotrecogin alfa and fondaparinux. The main oral blood thinners used is warfarin. Some blood thinners like heparin, sodium citrate, sodium oxalate and sodium edetate are also used to prevent blood clotting when it is collected either for blood tests or for transfusion.
From the global perspective, North America accounts for the largest market share for blood thinners owing to the rising demand of blood thinners owing to the increasing incidences of cardiac ailments. The high adoption rate of blood thinners in North America probably will help the region to retain the position of the leading region in the forecast years. However, other regions like Asia-Pacific, Middle East & Africa are expected to be probable markets in coming years. Across emerging markets, Asia Pacific and Latin America, the blood thinners market is expected to have a strong growth in the forecast years. Due to the extensive awareness about the blood thinners, these areas are most likely to be potential markets for blood thinners.
Currently, the global blood thinner market is highly competitive owing to the involvement of many established players. Some of the key players in the global blood thinner market are Bayer AG, Pfizer, Inc., Merck, Sanofi, Abbott Laboratories, Johnson and Johnson, Baxter International and AstraZeneca.